• Academia
    • Education
    • Research
    • Teaching experience
    • Other
  • Technical
    • Wet Lab Skills
    • Dry Lab Skills
    • Other software proficiency
  • Personal
    • Volunteering
    • Book written


About Me

I am passionate about molecular biology research, particularly in cancer biology and innate immunity.

Academic Background

My research focuses on unraveling the molecular complexity of protein methylation in cancer. My curiosity about public RNA-seq datasets from cancer patients led me to (self)-study bioinformatics, a field I found equally fascinating. Additionally, I have a strong foundation in molecular signaling, particularly inflammation-related transcription factor pathways such as NF-κB, AP-1, and IRF3.

Research Experience

As part of my combined Master-PhD study, I explored the molecular targets of plant extracts and bioactive compounds, investigating their potential anti-inflammatory properties.

Current Position

I am currently a lecturer at the Department of Histology and Cell Biology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, where I continue to engage in research and teaching in these fields.

Department of Histology and Cell Biology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Indonesia


Academia

Education

year what
2017 — 2022 PhD in Integrative Biotechnology, Sungkyunkwan University, South Korea
2012 — 2016 B Pharm, School of Pharmacy, Institut Teknologi Bandung, Indonesia

Research

type citation
Research Article Nur Aziz, Rollando, Eva Monica, FX Haryanto Susanto (2024). Aromatherapeutic Antibacterials: Comparative Study of 40 Essential Oils and Their Biofilm Inhibition in Pseudomonas aeruginosa ATCC9027 HAYATI Journal of Biosciences
Review Nur Aziz, Yo Han Hong, Han Gyung Kim, Ji Hye Kim, Jae Youl Cho (2023). Tumor-suppressive functions of protein lysine methyltransferases Experimental & Molecular Medicine
Research Article Eunji Kim, Laily Rahmawati, Nur Aziz, Han Gyung Kim, Ji Hye Kim, Kyung-Hee Kim, Byong Chul Yoo, Narayana Parameswaran, Jong-Sun Kang, Hoon Hur, Balachandran Manavalan, Jongsung Lee, Jae Youl Cho (2023). Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis International Journal of Biological Sciences
Research Article Lei Huang, Long You, Nur Aziz, Seung Hui Yu, Jong Sub Lee, Eui Su Choung, Van Dung Luong, Mi-Jeong Jeon, Moonsuk Hur, Sarah Lee, Byoung-Hee Lee, Han Gyung Kim, Jae Youl Cho (2023). Antiphotoaging and Skin-Protective Activities of Ardisia silvestris Ethanol Extract in Human Keratinocytes Plants
Research Article Nur Aziz (2022). Potential Roles of Methyltransferases Family 16 in Breast Cancer Syntax Literate
Research Article Young-Su Yi, Han Gyung Kim, Ji Hye Kim, Woo Seok Yang, Eunji Kim, Jae Gwang Park, Nur Aziz, Narayanan Parameswaran, Jae Youl Cho (2022). Syk promotes phagocytosis by inducing reactive oxygen species generation and suppressing SOCS1 in macrophage-mediated inflammatory responses International Journal of Immunopathology and Pharmacology
Research Article Nur Aziz, Eunji Kim, Yanyan Yang, Han Gyung Kim, Tao Yu, Jae Youl Cho (2022). p38-Dependent c-Jun Degradation Contributes to Reduced PGE2 Production in Sodium Orthovanadate-Treated Macrophages BMB Reports
Research Article Yo Han Hong, Nur Aziz [shared first authorships], Jae Gwang Park, Dagyeong Lee, Jin Kyeong Kim, Seung A.Kim, Wooram Choi, Chae Young Lee, Hwa Pyoung Lee, Ha Thi Huyen Trang, Han Gyung Kim, Young-Jun Jeon, Bokyoung Kim, Younghoon Kim, Kyung-Hee Kim, Byong Chul Yoo, Jeung-Whan Hang, Narayana Parameswaran, Jae Youl Cho (2022). The EEF1AKMT3/MAP2K7/TP53 axis suppresses tumor invasiveness and metastasis of gastric cancer Cancer Letters
Research Article Kon Kuk Shin, Sang Hee Park, Hye Yeon Lim, Laura Rojas Lorza, Nurinanda Prisky Qomaladewi, Long You, Nur Aziz, Soo Ah Kim, Jong Sub Lee, Eui Su Choung, Jin Kyung Noh, Dong-Keun Yie, Deok Jeong, Jongsung Lee, Jae Youl Cho (2022). In Vitro Anti-Photoaging and Skin Protective Effects of Licania macrocarpa Cuatrec Methanol Extract Plants
Research Article Young-Su Yi, Han Gyung Kim, Ji Hye Kim, Woo Seok Yang, Eunji Kim, Deok Jeong, Jae Gwang Park, Nur Aziz, Suk Kim, Narayanan Parameswaran, Jae Youl Cho (2021). Syk-MyD88 Axis Is a Critical Determinant of Inflammatory-Response in Activated Macrophages Frontiers in Immunology
Research Article Laily Rahmawati, Nur Aziz, Jieun Oh, Yo Han Hong, Byoung Young Woo, Yong Deog Hong, Philaxay Manilack, Phetlasy Souladeth, Ji Hwa Jung, Woo Shin Lee, Mi Jeong Jeon, Taewoo Kim, Mohammad Amjad Hossain, Jinwhoa Yum, Jong-Hoon Kim, Jae Youl Cho (2021). Cissus subtetragona Planch. Ameliorates Inflammatory Responses in LPS-induced Macrophages, HCl/EtOH-induced Gastritis, and LPS-induced Lung Injury via Attenuation of Src and TAK1 Molecules
Research Article Laily Rahmawati, Sang Hee Park, Dong Seon Kim, Hwa Pyoung Lee, Nur Aziz, Chae Young Lee, Seung A Kim, Seok Gu Jang, Dong Sam Kim, Jae Youl Cho (2021). Anti-Inflammatory Activities of the Ethanol Extract of Prasiola japonica, an Edible Freshwater Green Algae, and Its Various Solvent Fractions in LPS-Induced Macrophages and Carrageenan-Induced Paw Edema via the AP-1 Pathway Molecules
Research Article Woo Seok Yang, Han Gyung Kim, Eunji Kim, Sang Yun Han, Nur Aziz, Young-Su Yi, Sunggyu Kim, Yunmi Lee, Byong Chul Yoo, Jeung-Whan Han, Narayanan Parameswaran, Ji Hye Kim, Jae Youl Cho (2020). Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses Cells
Research Article Nur Aziz, Yo Han Hong, Min Kyeong Jo, Jin Kyeong Kim, Kyung-Hee Kim, Hassan Ashktorab, Duane T. Smoot, Hoon Hur, Byong Chul Yoo, Jae Youl Cho (2020). Molecular Signatures of JMJD10/MINA53 in Gastric Cancer Cancers
Research Article Nur Aziz, Young-Gyu Kang, Yong-Jin Kim, Won-Seok Park, Deok Jeong, Jongsung Lee, Donghyun Kim, Jae Youl Cho (2020). Regulation of 8-Hydroxydaidzein in IRF3-Mediated Gene Expression in LPS-Stimulated Murine Macrophages Biomolecules
Review Jae Gwang Park, Nur Aziz [shared first authorships], Jae Youl Cho (2019). MKK7, the essential regulator of JNK signaling involved in cancer cell survival: a newly emerging anticancer therapeutic target Therapeutic Advances in Medical Oncology
Research Article Kon Kuk Shin, Jae Gwang Park, Yo Han Hong, Nur Aziz, Sang Hee Park, Sunggyu Kim, Eunji Kim, Jae Youl Cho (2019). Anti-Inflammatory Effects of Licania macrocarpa Cuatrec Methanol Extract Target Src- and TAK1-Mediated Pathways Evidence-Based Complementary and Alternative Medicine
Research Article Yo Han Hong, Young-Su Yi, Sang Yun Han, Nur Aziz, Han Gyung Kim, Sang Hee Park, Mohammad Amjad Hossain, Kwang Soo Baik, Su Young Choi, Jongsung Lee, Jong-Hoon Kim, Jae Youl Cho (2019). Morinda citrifolia noni water extract enhances innate and adaptive immune responses in healthy mice, ex vivo, and in vitro Phytotherapy Research
Research Article Nurinanda Prisky Qomaladewi, Nur Aziz, Mi-Yeon Kim, Jae Youl Cho (2019). Piper cubeba L. Methanol Extract Has Anti-Inflammatory Activity Targeting Src/Syk via NF-?B Inhibition Evidence-Based Complementary and Alternative Medicine
Review Nur Aziz, Mi-Yeon Kim, Jae Youl Cho (2018). Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies Journal of Ethnopharmacology
Research Article Nur Aziz, Young-Jin Son, Jae Youl Cho (2018). Thymoquinone Suppresses IRF-3-Mediated Expression of Type I Interferons via Suppression of TBK1 International Journal of Molecular Sciences
Research Article Neng Fisheri Kurniati, Afrillia Nuryanti Garmana, Nur Aziz (2017). Antibacterial and Antifungal Activities of Ethanol Extract of the Roots, Flowers, and Leaves of Turi (Sesbania grandiflora L. Poir) Acta Pharmaceutica Indonesia
year_begin what
2018 Korean Society for Biochemistry and Molecular Biology (KSBMB) International Conference 2019: Depletion of MINA53 suppresses proliferation and survival of gastric cancer cells by regulating mitogen-activated protein kinase signaling pathway, Jeju, South Korea

Teaching experience

year what
2024 — Now Medicine - Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Indonesia
Universitas Gadjah Mada
2022 — 2024 Pharmacy Program - Faculty of Science and Engineering, Universitas Ma Chung, Indonesia
Universitas Ma Chung
2018 — 2020 Laboratory assistant: Molecular Immunology
Sungkyunkwan University
2016 Laboratory assistant: Integrated Pharmacology
Institut Teknologi Bandung

Other

year_begin what
2017 Outstanding Foreign Student Scholarship Award : Full Tuition Fee for Combined Master and PhD Course, Sungkyunkwan University, South Korea
year_begin what
2015 Isolation and purification of hGCSF from Escherichia coli, Laboratory of Protein Engineering and the Development of Drug Delivery System, Center for Biotechnology Research. Indonesian Institute of Science (LIPI)

Technical

Wet Lab Skills

what
- Gene cloning and mutagenesis incl. point mutation, insertion, or deletion
- Recombinant protein expression and purification from E. Coli .
- Genomic DNA preparation and total RNA extraction .
- cDNA synthesis, conventional PCR, and Real-Time PCR analysis .
- Mammalian cell cultures .
- Cell viability assay .
- Gel electrophoresis, Immunoblotting, and gels staining .
- Immunoprecipitation and pulldown assay .
- Enzyme assay : In viro kinase and methyltransferase assay, ELISA
- In-vitro tumorigenic responses phenotyping : proliferation, migration, invasion, colony formation assay, and EMT signature analysis
- In-vivo tumor xenograft mouse model
- Gene overexpression via transfection
- Transcription activity reporter assay .
- Generation of lentiviral particle for viral transduction
- Generation of transient/stable knockdown cell lines using siRNA/shRNA

Dry Lab Skills

what
- Big data analysis and data wrangling in R (using tidyverse and dplyr)
- Public dataset analysis of microarray/RNA sequencing from Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and GTEx
- Differential gene expression analysis DGEs analysis using DESeq2 or limma
- Functional gene enrichment analysis (GSEA)
- Statistical analysis and data visualization in R (main: ggplot2, pheatmap), or Python (matplotlib)
- Sequence aligments and phylogenetic analysis .
- Protein 2D / 3D structure visualization : customization using BIOVIA Discovery Studio and Chimera

Other software proficiency

what
- Paper figuring and illustration with Adobe Illustrator, Adobe Photoshop, and Corel Draw
- Basic office tools ie. Microsoft Office Word, Excel, and PowerPoint
- Web development (HTML using R markdown, GitHub Pages, Netlify)

Personal

Volunteering

year what
2013 — 2016 Teaching
Bimbel SOSMAS KAM BG-ITB
teaching elementary and junior high school students (weekly)

Book written

year what
2020 Title : Dongeng Kecil (A Small Tale)
Self-Published
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